Announcements and non-science news
Submitted by Fatemeh Saberia, Samad Jahandideh
Department of Medical physics and Bio-medical Engineering,
Shiraz University of Medical Sciences, Shiraz, Iran
During recent years, due to different devices used in industry an increment in the number of investigations related to Electromagnetic Field (EMF) effects composed of a wide range of parameters such as polarization, exposure duration, and exposure profiles has been reported to affect biological systems in the field of bioelectromagnetics [Anderson, 1993; Cleary, 1993; Frey, 1993; Hong, 1995], but so far no agreement on the effect of different parameters in experimental designs in relation to exposure conditions have been reached.
Up to now, so many investigations have been reported in relation to physical mechanisms of EMF's bioeffecs [Binhi, 2006; Binhi, 2007; Vincze et al., 2008; Liboff, 2009; Muehsam and Pilla,2009a; Muehsam and Pilla 2009b]. On the other hand, although a huge number of researches have been done in the field of bioelectromagnetics, but no specific database has been designed to facilitate search for collecting specific databases in the specific subjects, such as effect of EMF on mutagenesis, cell proliferation, apoptosis and so on, to analyze obtained results. A well-known example of such database is Protein Data Bank (PDB) in the field of bioinformatics. The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies [Berman et al., 2002].
Recently we published two papers based on a collected database including all experiments on melatonin excretion patterns in the rat exposed to EMF [Jahanndideh et al., 2010; Jahandideh and Abdolmaleki, In press]. In these papers effect of EMF on melatonin excretion patterns were analyzed and predicted using algorithmic and non-algorithmic predictor models which showed valuable results. Such predictor models are promising and may play a useful role in defining guidelines for experimental designs relating to exposure conditions.
In conclusion, analysis and establish of predictor models on the bioelectromagnetic data could result in finding a relationship between the exposure conditions and different biological processes. This could in turn be useful in the development of treatments for some diseases by recognizing the possible positive effects of EMF. In addition, understanding how different magnitudes of electromagnetic fields affect the biological systems could help identify the harmful effects of naturally occurring electromagnetic fields on living organisms.
Dr. Jahandideh contact information: Tel: 0098-917-7372417, firstname.lastname@example.org
Anderson LE. 1993. Biological effects of extremely low-frequency electromagnetic fields: In vivo studies. Am Ind Hyg Assoc J 54:186–196.
Berman HM, Battistuz T, Bhat TN, Bluhm WF, Bourne PE, Burkhardt K et al. 2002. The Protein Data Bank. Acta Crystallog Sect D 58:899–907.
Binhi VN, Rubin AB. 2007. Magnetobiology: the kT paradox and possible solutions. Electromagn. Biol. Med. 26(1):45-62.
Binhi VN. 2006. Stochastic dynamics of magnetosomes and a mechanism of biological orientation in the geomagnetic field. Bioelectromagnetics 27(1):58-63.
Cleary SF. 1993. A review of in vitro studies: Low-frequency electromagnetic fields. Am Ind Hyg Assoc J 54:178–185.
Frey AH. 1993. Electromagnetic field interactions with biological systems. FASEB J 7:272–281.
Hong FT. 1995. Magnetic field effects on biomolecules, cells, and living organisms. Biosystems 36:187–229.
Jahandideh S, Abdolmaleki P, Movahedi MM. 2010. Comparing performances of logistic regression and neural networks for predicting melatonin excretion patterns in the rat exposed to ELF magnetic fields. Bioelectromagnetics 31:164–171.
Jahandideh S, Abdolmaleki P. Prediction of melatonin excretion patterns in the rat exposed to ELF magnetic fields based on support vector machine and linear discriminant analysis. Micron (In press)
Muehsam DJ, Pilla AA. 2009a. A Lorentz model for weak magnetic field bioeffects: part I--thermal noise is an essential component of AC/DC effects on bound ion trajectory. Bioelectromagnetics 30(6):462-75.
Muehsam DJ, Pilla AA. 2009b. A Lorentz model for weak magnetic field bioeffects: part II--secondary transduction mechanisms and measures of reactivity. Bioelectromagnetics 30(6):476-88.
Liboff AR. 2009. Electric polarization and the viability of living systems: ion cyclotron resonance-like interactions. Electromagn. Biol. Med. 28(2):124-34.
Vincze G, Szasz A, Liboff AR. 2008. New theoretical treatment of ion resonance phenomena. Bioelectromagnetics 29(5):380-386.
The 2010 d'Arsonval award was presented to Shoogo Ueno (shown here with President Michael Murphy and Executive Director Gloria Parsley), Professor Emeritus at the University of Tokyo, Professor at the Graduate School of Engineering at Kyushu University, and Dean of the Faculty of Medical Technology at Teikyo University in Fukuoka, Japan. In addition, he has mentored and encouraged many students who have, in turn, contributed to the success of The Bioelectromagnetics Society. He is shown below with colleagues (left to right) Jim Lin, Andrew Wood, Mrs. Ueno, Jeff Carson, Professor Ueno, Frank Barnes, Andrei Pahkomov, and Michael Murphy.
Dr. Ueno's work encompasses studies in transcranial magnetic stimulation, magnetoencephalography, MRI studies of impedance and conductivity, cancer therapy with pulsed magnetic fields, the influence of magnetic fields on cell orientation and growth, and changes in ferritin and iron release and uptake. His acceptance speech described the key influences on his early work by Professors Shigeaki Matsuoka, and Yutaka Oomura. He noted that at the International Conference on Medical and Biological Engineering held in Ottawa, Canada, in August 1976, his comment to Dr. Ake Oberg that the method Oberg presented was not magnetic stimulation but instead might be capacitive stimulation lead to an invitation to collaborate at Oberg's lab. This in turn lead to a range of nerve excitation studies under magnetic fields, including the surprising effect that transcranial stimulation can control detailed finger movement so well that someone without piano training could be made to play Chopin under the appropriate magnetic field stimulation!
Further work included studies of how pulses applied in one hemisphere of the brain might appear as a signal in the other hemisphere, suggesting a method for studying intra- and interhemispheric connectivity. He then went on to find different activation patterns in the brains of speakers with differing native languages reading Kanji and Kana words.
The full range of Dr. Ueno's studies will be described later in an article to appear in the Bioelectromagnetics journal.
BEMS members Andrei Pakhomov, Marko Markov, and Damian Miklavcic are the co-editors of one of the newest books from CRC Press: Advanced Electroporation Techniques in Biology and Medicine. Published in June 2010 (ISBN # 978-1-4398-1906-7) the book features "the most recent experimental findings and theories related to permabilization of biomembranes by pulsed electric fields." It includes articles ranging from the physiochemical theory of membrane poration and transfer of biogenic agents through more detailed models of electroporation effects in lipid systems to the mechanisms of electroporation in biological tissues and the technical considerations, and specific clinical applications of electroporation. Specifically, it features discussions of:
- the contemporary physical chemical theory of membrane electroporation
- appropriate applications of dyes and fluorescent probes to test the efficiency and selectivity of molecular transport through permeabilized membranes
- a recently proposed molecular dynamics method of electroporation
- the impact of different physical parameters of the applied electric field on the efficiency of resulting electroporation
- basic processes and biophysical mechanisms of electrically mediated gene transfer
- results and experience with electrochemotherapy of cancer in animal models and humans
Additional information is available on the CRC Press website.
By nearly any measure, the 32nd Annual Meeting of the Bioelectromagnetics Society was a great success. The meeting was held at the Seoul Education Culture Center, also known as Hotel Seoul KyuYuk MunHwa HeoKwan, located near Citizen's Forest near Weemyeonsan mountain.
On Saturday evening, Local Organizing Committee Chair Nam Kim (Chungbuk National University), shown above with Jeong-Ki Pack (Chungnam National University) and YoonMyoung Gimm (Dankook University) welcomed attendees to Seoul during the President's Reception on the Han River.
Next, President Michael Murphy, his wife, Janet, and Local Organizing Committee Chair Nam Kim, with his wife HyeRhin Hong, and daughter Hanny Kim, toasted attendees as they enjoyed a range of Korean dishes.
Sunday's opening reception brought BEMS colleagues together in Geomungo Hall and provided a chance for colleagues to renew old friendships and make new professional contacts.
Here, former BEMS treasurer Robert Cleveland (center) and Lloyd Morgan (right) discuss their work with Dr. Chung-Sang Ryu, Deputy Director of the Radio Research Agency in Korea (left).
The Technical Program featured an opening Plenary session on Clinical Applications of Electric and Magnetic Fields focusing on electroporation and pulsed electric fields. Here, from the left, speaker Boris Rubinsky from the University of California at Berkeley joins session chairs Andrei Pakhomov and Rich Nuccitelli (who also spoke), speaker Luis Mir from the Laboratory of Vectorolgy and Anticancer Therapies in Paris, and Technical Program Chair, Dariusz Leszczynski.
A second Plenary session kicked off the day Tuesday, with presentations by Vitas Anderson, David Black, and Maila Hietanen on Occupational Exposures of EMF, particularly focusing on radio frequency fields. The spirted discussion initiated by these talks continued over lunch.
Following lunch, BEMS President Michael Murphy presented the d'Arsonval Award, The Bioelectromagnetics Society's highest honor, to Shoogo Ueno for his work studying magnetic field effects on brain tissue for more than forty five years. A separate article in this newsletter highlights this award, and the full text of Dr. Ueno's acceptance speech will be published in an upcoming issue of the Bioelectromagnetics journal.
Social Event and Sponsor Recognition
The social event is also traditionally the time that The Society honors its sponsors. This year's sponsors included:
- Gold sponsors: Korea Radio Promotion Agency and Mobile Manufacturers Forum
- Silver sponsors: Electric Power Research Institute (EPRI, USA), Korea Electric Power Corporation (KEPCO), National IT Industry Promotion Agency (NIPA, Korea), Nikken, and the United States Air Force Research Laboratory.
- Bronze sponsors: KT (Korea), LG Telecom, National Research Foundation of Korea, Seoul Tourism Organization, SK Telecom, GSM Association, Korean Institute of Electromagnetic Engineering and Science, Korea Tourism Organization, and Lawson Health Research Institute.
The Society deeply appreciates the contributions from each of these organizations, without which the meeting would not have been possible.
Tuesday night's social event continued with a presentation by Sa Mul Poong Yeon of a Korean folk music tradition, Pungmul, with drumming, music, and performers wearing sangmo, or hats with long ribbon attached that spin and flip in intricate patterns as performers move their heads. Pungmul is rooted in the collective farming culture of Koreaand originally played a role in community building events.
In contrast to this, the next presentation by the Black & Scale Crew featured Korea's newest form of dance: B-boy, a term derived from "beat boy" because the dancers move to a specific beat. Commonly called breakdancing, this style has evolved from its early African roots through adoption by Black and Latino young men in the South Bronx (NY, USA) to a worldwide competition in which Korea now boasts one of the top teams.
At the conclusion, both Sa Mul Poong Yeon (Pungmul) and Black & Scale Crew (B-boy) performed together - the first time these two dance forms have been brought together, according to conference organizers.
More of Technical Session
Wednesday was a relatively short day, featuring a lively plenary discussion on thermal versus non-thermal effects. Frank Barnes kicked off the discussion by noting that there are several different definitions of temperature. Marvin Ziskin then discussed mechanisms for distinguishing between thermal and non-thermal effects. His presentation was followed by Niels Kuster, whose talk explored whether existing specific absorption rate (SAR) standards are appropriate in light of recent studies, concluding that they are not.
Thursday's plenary on the safety of future technologies began with a look at improvements in MRI resolution with increasing magnetic fields (to 7 Tesla) by Professor Kan-Hee Cho of the Gachon University of Medicine & Science and the University of California at Irvine. This talk was followed by a presentation by Dr. Joungho Kim of the Korean Advance Institute of Science and Technology (KAIST) on a roadway powered vehicle system now in use in Seoul.
Bernard Veyret of the University of Bordeaux wrapped up the session with a look at how media portrayals of risks prior to complete scientific assessments of new technologies may be distorted.
Joungho Kim of KAIST is shown here with plenary session co-chair Nam Kim.
Annual Business Meeting
At the annual business meeting, outgoing President Michael Murphy thanked Technical Program Chairs Nam Kim and Dariusz Leszczynski, as well as outgoing board members Vijay, Phil Chadwick (who retires as Secretary and returns to the board as Treasurer), Carl Blackman, Maren Fedrowitz, Indira Chatterjee, and Chiyoji Ohkubo. He then presented the gavel to incoming President Jeff Carson (shown below).
Concluding Technical Session
Friday's plenary session examined the long awaited results of the Interphone epidemiology study of whether cell phone use is associated with brain tumors. Discussions focused on a variety of issues related to methodology as well as results, with different points of view by plenary speakers Bruce Armstrong, Jørn Olsen, and Joachim Schüz, shown left to right below.
Jeff Carson 2010
Prof. JeongHo Kim(KAIST), Nam Kim
Dr. Chung Sang Ryu (Radio Research Agency, Korea), Dr. A.E. Lee(ETRI), Prof. Jong-Yoon Hwang(Kangwon Nat'l Univ.), Prof. Yoon-Won Kim(Hallym Univ.), Prof. Jeong-Ki Pack(Chungnam Nat'l Univ.), Prof. Nam Kim, Prof. Young-Hwan Ahn(Ajou Univ.), Prof. YoonMyoung Gimm(Dankook Univ.)
Nam Kim, Prof. Jeong-Ki Pack (Chungnam Nat’l Univ.), Dr. M. Murphy
Nam Kim, ?? , Murphy ---> would you ask to Dr. Murphy or Gloria?